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Join the PROMETHEUS consortium, a four-year EIC Pathfinder project developing a next-generation multimodal, explainable and multi-agent AI system for prostate cancer diagnosis and treatment selection (https://cordis.europa.eu/project/id/101306686). The consortium brings together leading European partners with multicentre patient cohorts, including Heidelberg University Hospital, DKFZ, Erasmus MC Rotterdam, Radboudumc Nijmegen, Karolinska Institutet and Umeå University.Within the group of PD Dr. Magdalena Görtz (https://www.dkfz.de/en/multiparametric-methods-for-early-detection-of-prostate-cancer), you will lead the development of an AI agent for treatment selection that combines longitudinal clinical data, imaging, outcome prediction and knowledge-based reasoning. The goal is to move beyond isolated prediction models towards an integrated agentic system that can model patient trajectories, compare treatment strategies and generate transparent, clinically meaningful decision support.
- Job-ID: V000016163
- Field of application: Urologische Klinik
- Location: Heidelberg
- Start date: 01.10.2026
- Job Category: Science and teaching
- Working hours: full-time (100%)
- Published: 07.09.2026
- Limitation:Temporary (30.09.2030)
- Contract:TV-L
Your Responsibilities
- Multimodal data integration and preprocessing: Harmonize and integrate longitudinal clinical data, imaging, pathology and outcome data
- Multi-agent and predictive AI development: Develop machine-learning components for patient-trajectory modelling, recurrence and survival prediction, and integrate them into the PROMETHEUS multi-agent
- Agent interaction, explainability and uncertainty: Contribute to architectures that combine specialized AI components, knowledge-based reasoning and clinically interpretable outputs; implement uncertainty estimation and human-in-the-loop mechanisms
- Validation and clinical translation: Perform internal and external validation, benchmark against established risk models and assess clinical utility across European cohorts
- Scientific communication and collaboration: Contribute to high-impact publications, presentations and close collaboration with clinicians, imaging experts and AI researchers in Heidelberg and across the European consortium
Your Profile
- Master's degree or PhD in Data Science, Bioinformatics, Computer Science, Computational Biology, Biostatistics, Medical Informatics, Mathematics, Physics, or a related discipline
- Excellent programming skills in Python and/or R
- Strong expertise in machine learning, deep learning and predictive modelling
- Experience working with multimodal, longitudinal or high-dimensional datasets
- Interest in or experience with multi-agent systems, agent orchestration, transformers, multimodal fusion, knowledge-grounded AI or clinical decision support systems
- Sound understanding of model validation, calibration and reproducible research practices
- Experience in explainable AI, survival analysis, medical imaging or healthcare AI is considered an advantage
- A proactive, independent and scientifically motivated mindset combined with excellent communication and collaboration skills in an interdisciplinary international environment
What We Offer
- Collectively agreed remuneration according to TV-L E13, attractive company pension scheme (VBL)
- Opportunity to work within a prestigious European research consortium at the forefront of AI and precision oncology
- Active role in developing novel AI technologies with direct relevance for clinical decision-making and patient care
- Access to unique multicentre datasets and state-of-the-art research infrastructure
- Close collaboration with internationally recognized experts in medicine, artificial intelligence and medical imaging
- 30 days vacation
- Sustainable travel: job ticket
- Family-friendly working environment: cooperative arrangements for childcare, subsidy for child vacation care, advice for employees with relatives in need of care
- Wide range of health, prevention and sports offers
Contact \& Application
For further information, please contact PD Dr. Magdalena Görtz, Senior Physician and Research Group Leader.
Advance the Future of Precision Oncology
We look forward to receiving your online application.
Urologische Klinik
PD Dr. Magdalena Görtz, Senior physician, Research group leader
Im Neuenheimer Feld 420
69120 Heidelberg
[email protected]
Note: The UKHD is subject to the provisions of the Infektionsschutzgesetz. Therefore, a valid measles immunity certificate is required for all persons employed at the UKHD.
The UKHD embraces diversity and values diversity.
Regardless of age, gender, sexual identity, disability, origin or religion, we offer everyone the same opportunities. If one gender is underrepresented in a particular area, we place particular emphasis on counteracting this imbalance. If they have the same aptitude, qualifications and professional performance, we give priority to people with severe disabilities when considering them for vacancies.
Apply online now: https://karriere.klinikum.uni-heidelberg.de/index.php?ac\=application\&jobad_id\=29009
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